| Date | Apr 29 | Total matches | 8 | 
| Men's matches | 4 | Women's matches | 4 | 
| Singles matches | 8 | Tag Team matches | 0 | 
| Trio Matches | 0 | Other Matches | 0 | 
This episode of SmackDown took place on April 29, 2022 and featured 8 matches on the card. A majority of the matches ended by pinfall, submission, or the rules stipulated by the match, but 1 match had no clear winner. Only one championship, the Intercontinental Championship, was defended on the card.
The matches featured 16 wrestlers, highlighted by Ricochet, Ronda Rousey, Sheamus and Xavier Woods.
Predictability
            
                Mostly Predictable
(7 of 8 Matches)
            
        
Competitions
            
                More Singles
Less Tag
            
        
Diversity
            
                Usual Mens
More Womens
            
        
Balance of Power
            
                Faces won the card with 5 wins (of 8 matches).
(Heels won 2 matches)
            
        
| Women's Singles I Quit Challange | 
| 4-0-1 (Overall: 4-1-1, Last 5: 3-1-1) Win Probability: 61.4% | 
| 3-1-1 (Overall: 3-1-1, Last 5: 3-1-1) Win Probability: 38.6% | 
| Match ended in a No Contest | 
| Women's Singles I Quit Challange | 
| 2-1 (Overall: 3-1, Last 5: 3-1) Win Probability: 69.7% | 
| 0-2 (Overall: 0-2, Last 5: 0-5) Win Probability: 30.3% | 
| Men's Singles | 
| 3-1 (Overall: 8-1, Last 5: 4-1) Win Probability: 62.5% | 
| 1-3 (Overall: 4-8, Last 5: 1-4) Win Probability: 37.5% | 
| Men's Singles | 
| 4-0 (Overall: 4-3, Last 5: 4-1) Win Probability: 64.2% | 
| 1-3 (Overall: 6-3, Last 5: 3-2) Win Probability: 35.8% | 
| Women's Singles | 
| 4-4 (Overall: 11-4-1, Last 5: 4-1) Win Probability: 62.5% | 
| 0-2 (Overall: 1-5-1, Last 5: 0-4-1) Win Probability: 37.5% | 
| Women's Singles (Squash) | 
| 1-0 (Overall: 1-0, Last 5: 1-0) | 
| Men's Singles  | 
| Champion 7-5 (Overall: 7-8, Last 5: 3-2) Win Probability: 73.0% | 
| 0-1 (Overall: 0-4, Last 5: 0-5) Win Probability: 27.0% | 
| Men's Singles Steel Cage | 
| 9-0 (Overall: 11-0-1, Last 5: 5-0) Win Probability: 89.3% | 
| 1-8 (Overall: 1-8, Last 5: 0-5) Win Probability: 10.7% |